The Diagnostic Accuracy of Dermoscopy for Scabies

BACKGROUND: Scabies is a contagious skin infestation characterized clinically by nocturnal pruritus, visible burrows and contagiousness. Dermoscopy has been suggested as an alternative for diagnosing scabies. But, there have been few well-designed studies evaluating the diagnostic accuracy of dermoscopy. OBJECTIVE: We tried to confirm the diagnostic accuracy of dermoscopy for diagnosing scabies. We also tried to demonstrate specific circumstances in which dermoscopic identification of mites ("with dermoscopy") is more useful in diagnosing scabies, and to identify the specific clinical findings that could be used as a possible marker in diagnosing scabies. METHODS: We compared the scraping procedure "with dermoscopy" and "without it" in 49 patients, measuring the duration and outcome of each procedure. Also, we tried to find the specific clinical factors associated with our objects. RESULTS: The skin scraping "with dermoscopy" was superior to "without it" with respect to the duration and accuracy of the procedure. A history of previous steroid treatment was associated with the superiority of dermoscopy. The correlation between the presence of visible burrows and the positive outcomes of "with dermoscopy" was statistically significant. CONCLUSION: Skin scraping with dermoscopy is implicated as the diagnostic method of choice for scabies at the present time. Dermoscopy is especially useful in diagnosis of incognito scabies. In addition, the presence of visible burrows could be a reliable positive marker of scabies in the absence of dermoscopy or microscopy data.

Cutaneous Lymphoid Hyperplasia Which Developed after Allergy Skin Test of Antibiotics / 대한피부과학회지

Cutaneous lymphoid hyperplasia (CLH, pseudolymphoma) refers to a heterogeneous group of benign reactive T- and/or B-cell lymphoproliferative diseases of the skin, that resemble cutaneous lymphoma both clinically and histologically. Despite the unknown causes of CLH development, various stimuli can induce CLH, such as medications, infections, insect bites, photosensitivity and foreign agents. To date, there has been no reported case of CLH development after an allergy skin test of antibiotics. Thus, we report a patient who developed CLH following an allergy skin test of antibiotics. He was a 21-year-old man who presented with 1.5x1.5 cm sized erythematous plaque with yellowish crusts on his right forearm that showed features of a CLH, based on histopathologic assessment.

Multiple Lichen Striatus in an Adult / 대한피부과학회지

Lichen striatus is an uncommon, self-limiting dermatosis that is characterized by linearly distributed eruptions that follow Blaschko's lines. It usually occurs unilaterally, but few cases of bilateral or multilinear eruptions have also been reported. In addition, lichenstriatus is commonly seen in children and rarely affects adults. We report a case of 29-year-old woman with multiple, unilateral lichen striatus on the right abdomen and right chest that was treated successfully with topical tacrolimus.

A Case of Chronic Mucocutaneous Candidiasis Occurring in a Patient with Scrofuloderma-like BCGitis / 대한의진균학회지

Chronic mucocutaneous candidiasis (CMC) consists of several clinical syndrome characterized by chronic, treatment-resistant, superficial candidal infections of skin, nails and oropharynx. The patients with CMC usually have other manifestations including non-candidal infections, endocrinopathies and autoimmune diseases. These findings suggest that patients with CMC have multiple or complex abnormalities in their immune systems, especially of cell mediated immunity. The scrofuloderma or scrofuloderma-like BCGitis is used to describe the skin reaction and enlargement of regional lymph node with suppuration. In contrast to chronic mucocutaneous candidiasis, BCGitis does not suggest underlying host immune defect in most cases. In our knowledge, there is no report about scrofuloderma-like BCGitis and chronic mucocutaneous candidiasis occurring in the same patient. Herein, we report a case of chronic mucocutaneous candidiasis associated with scrofuloderma-like BCGitis.

Chondroid Syringoma Occurring in an Adolescent Girl / 대한피부과학회지

Chondroid syringoma is a myxoid tumor of the skin and the reported incidence of this is 0.098% among all the primary skin tumors. This tumor generally occurs in middle or old aged patients. A 15-year-old woman presented with a 2-year history of a 0.4x0.4 cm sized whitish papule on her nasolabial fold. The tumor was diagnosed as chondroid syringoma by histologic examinations. We present here a case of chondroid syringoma in an adolescent girl, and such a case has not been previously reported in the Korean medical literature.

A Case of Transient Acrodermatitis Enteropathica with a Normal Serum Zinc Level Localized on the Anogenital Area / 대한피부과학회지

A male full-term infant who had been breast-fed since birth developed an erythematous eroded eruption involving the anogenital area at 1 month of age, and this lesion did not respond to treatment with topical corticosteroids and antimicrobials. He was first seen at our office at 9 months of age. At that time, he had continuous diarrhea, but he had no alopecia, nail dystrophy or acral skin lesions. His serum zinc level was normal and his mother's breast milk zinc level was also normal, but it was not enough for his zinc metabolism. His clinical symptoms and skin lesions were dramatically improved with administering zinc.

Acute Generalized Exanthematous Pustulosis in a 10-month-old Infant / 대한피부과학회지

Acute generalized exanthematous pustulosis (AGEP) is an uncommon aseptic pustular eruption that usually follows recent administration of oral or parenteral drugs. Characteristic AGEP features include the sudden onset of fever with widespread erythematous eruption, rapidly progressing to a fine, non-follicular, micropustular rash. The illness usually resolves spontaneously with fever and pustulation clearing within 15 days, sometimes followed by desquamation. Histopathology shows non-follicular spongiotic pustules in the epidermis filled with neutrophils, a mixed perivascular infiltrate of neutrophils and occasional eosinophils with papillary dermal edema. We describe a 10-month-old boy with AGEP secondary to exposure to amoxicillin. This is an uncommon condition in children.

A Case of Eruptive Vellus Hair Cysts That Developed on the Labium Major

Eruptive vellus hair cysts are asymptomatic, flesh-colored- to-bluish, 1-to-4 mm-sized papules that are usually located on the chest and extremities of children and young adults. Histologically, small cysts are observed in the mid-dermis and these cysts contain multiple hair shafts and keratinous materials. We report here on a case of eruptive vellus hair cysts that developed on a rare site, the labium major.

A Case of Verrucous Carcinoma with Subcutaneous Abscess on the Buttock / 대한피부과학회지

Verrucous carcinoma is an uncommon low-grade variant of squamous cell carcinoma. It is clinically characterized by its verrucous and fungating appearance and it is histologically characterized by well-differentiated epithelial proliferations that push the underlying dermis. There are some reports of verrucous carcinoma associated with abscess or fistula, but there have been no case reports of verrucous carcinoma complicated with a subcutaneous abscess involving the adjacent tissue in Korea. We report here on a case of verrucous carcinoma that presented with focal verrucous nodule infiltrating the adjacent subcutaneous tissue with diffuse subcutaneous abscess formation.

A Case of Human Infestation of Canine Scabies / 대한피부과학회지

Transmission of animal scabies to human is probably rare because of the relative host specificity of the mites. However, recurrent exposure to animal scabies mites can produce troublesome and diagnostically puzzling lesions. We report herein on a human infestation of canine scabies and this occurred in a 26-year-old male who presented with a 4-month history of severe pruritic skin lesions. His puppy was diagnosed with scabies infestation by a veterinarian two months previously. Since that time, he no longer raised the puppy. Microscopic examination of a mineral oil preparation after scraping the papules revealed a mite. He was diagnosed with canine scabies.